The process for preparation of seratrodast by condensation reaction from 2,3,5-trimethyl hydroquinone and 7-hydroxy-7-phenylheptanoic acid,which was prepared by chlorination,F-C acidylation,hydrolysis and reduction from ethyl pimelate,was studied.
英
美
- 研究了以庚二酸单乙酯为原料;经酰氯化、傅-克酰基化、水解以及还原得到7-羟基-7-苯基庚酸;再与三甲基氢醌反应制得塞曲司特的工艺.