The present study provides a strong demonstration that beta -AR activation facilitates excitatory synaptic transmission in the mPFC through both pre- and post-synaptic mechanisms.

• 本工作首次提供了直接的电生理证据，表明beta受体通过突触前和突触后的双重机制，易化内侧前额叶皮层的兴奋性突触传递。