The present results indicate that BMP-2 shows more influence on neuronal differentiation of neural stem cells than EGF and Ctrl and there is no relationship between the increase of neurons induced with BMP-2 and Notch signaling.

• 结果提示,BMP-2对神经干细胞分化为神经元的诱导作用强于EGF和自主分化,其分化为神经元的比例增加与Notch信号分子的表达水平无关。