The plasma drug levels can be significantly elevated resulting in a relative higher level in the CSF by using HD-AraC, which may be the pharmacological basis of good outcomes obtained in clinical treatment.

• 应用HD- AraC治疗可明显提高药物血浓度,脑脊液中也能维持较高的药物浓度水平,是达到显著临床疗效的药理学基础。