The plasma concentration-time curves of olmesartan were fitted to a one-compartment model in 29 healthy volunteers after a oral olmesartan medoxomil tablet in single dose (20, 40, 80 mg), and the Cmax, AUC were dose dependent.

• 健康人单剂量口服奥美沙坦酯片后,体内奥美沙坦的药动学符合有滞后时间的一房室模型,Cmax与AUC与服药剂量呈线性相关。