The pIRES-CD and pIRES-TK expression plasmids are successfullyconstructed and expressed in ACC-2 cells,which offers a pathway for research on gene therapy of tumors.

• 成功构建CD和TK基因的重组真核表达质粒pIRES-CD及pIRES-TK,将其转染ACC-2细胞后能分泌性表达CD和TK,为肿瘤基因治疗的研究提供一定途径。