The mutagenicity of do-mestic Vesnarinone (OPC-8212) waw stud-ied by Ames test, micronucleus test ofNIH mouse bone marrow and chromosomeaberration assay in CHL cells.

• 作者应用鼠伤寒沙门氏菌回复突变试验,小鼠骨髓红细胞微核试验及CHL细胞染色体畸变试验,对维那利酮(OPC-8212)的诱变性进行了试验研究,其结果均为阴性。