The mRNA and protein expressions of cyclin D1 decreased after HCT116 cells were exposed to CAPE for 24, 48 h, which were in a concentration- and time-dependent manner.

• 2 5、5 0、10mg LCAPE处理HCT116细胞2 4、48h后cyclinD1蛋白和mRNA表达均降低,呈剂量和时间依赖性。