The level of AFP in pregnant women with acephaly, spina bifida and meningocele, cleft palate and lip, abdomen cleft extrogastrulation, abortion? dead fetus was extremely increased.

• (2 )无脑儿、脊柱裂脑脊膜膨出、腹裂、唇腭裂、自然流产、死胎孕妇血清AFP明显升高。