The jaundice may fluctuate in a certain range, accompanied by itchy skin, weight loss, poor spirit.The ascites, oliguria and hepatic coma may occurr late due to liver failure.

 
  • 少数病人抗核抗体及抗平滑肌抗体可为阳性,但抗线粒体抗体阴性,这可与原发性胆汁性肝硬化区别。
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