The insertion/deletion polymorphism of the ACE gene might be an independent risk factor for development of HCM in the Han people and DD genotype of ACE gene a new molecular biological marker for HCM accompanied by higher morbidity and risk of VA.

• ACE基因I/D多态性是汉族国人HCM发生、发展的独立危险因素,ACE基因DD型是HCM并发室性心律失常高发性和高危性的一个分子生物学指标。