The increase of SGT mRNA is also observed in 7721 cells undergoing apoptosis, knockdown the expression of endogenous SGT contributes to the decrease of apoptosis of 7721 cells.

• 分别用CHX和STS诱导细胞凋亡的过程中,SGT的mRNA水平也有一定程度升高; 用RNAi技术下调SGT的内源性表达可减少化学因子引发的细胞凋亡。