The inactivation of DCC gene is an important factor which influences prognosis of large intestinal cancer. The mechanism of DCC gene inactivation is mainly DCC sequence mutation.

 
  • 结论:DCC基因失活可能是影响大肠癌预后的重要因素之一;肝转移者发生DCC表达失活的主要机制是发生了基因突变.
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