The immunostaining of GRP78 coupled with confocal microscopy demonstrated the granular and perinuclear expression as normal ER distribution in cells under normal growing conditions.

• 利用共轭焦萤光显微镜及免疫萤光染色法，证明在正常细胞生长状况下，GRP78的免疫染色在细胞核附近的细胞质呈现颗粒分布，也就是一般内质网的分布图谱。