The hemoglobin disorders of thalassemia is the most prevalent group of human monogenic diseases,which results from globin protein chain peptide synthesis imbalance.

• 地中海贫血是最常见的单基因遗传病,它是由于珠蛋白肽链合成量之间不平衡导致,所以纠正珠蛋白肽链失衡成为地中海贫血治疗研究的关键。