The frequency of invasive fungal infections,especially for the yeast,has risen dramatically in recent years,increasing antifungal selection pressure and the emergence of antifungal resistance.

• 近年来真菌感染尤其是酵母样真菌感染的发病率和严重程度逐年上升,且随着耐药菌株的不断出现,抗真菌药物的选择受到限制。