The firing rate of the ZI in 6-OHDA-lesioned rats increases significantly, and this increasing can maintain one month at least, which may contribte to the pathophysiology of PD.

• PD大鼠ZI神经元的放电频率显著增高，且这种活动增强可以维持一个月之久，这可能在PD发病的病理生理变化中具有重要作用。