The factors that regulate the cell cycle include Cyclin, Cyclin-dependent kinase(CDK), Cyclin-dependent kinase inhibitor(CKI). CyclinDl is the major control switches in the G1 phase.

• 参与细胞周期调控的蛋白主要有：细胞周期蛋白(Cyclin)、细胞周期蛋白依赖性激酶(Cyclin-dependent kinase，CDK)、细胞周期蛋白依赖性激酶抑制因子(Cyclin-dependent kinase inhibitor，CKI)。