The expression of IR,IRS - 1 decreased in the hippocampal neuron in CPR rats,and early administration of neurotrophic factor-APP17 peptide could recover the expression of IR,IRS-1 to or approximately to the normal level.

• 心肺复苏大鼠海马神经元IR、IRS-1表达降低,复苏早期给予APP17肽干预可使其表达恢复正常或接近正常。