The expression and activity of the focal adhesion kinase on cultured Raji cells were regulated by Triptolide,and this regulation may be important in the tumor-pathogesis.

• 雷公藤内酯醇具有抗淋巴瘤细胞增殖效应,并同时降低FAK含量和活力,提示雷公藤内酯醇抗肿瘤效应可能与抑制黏着斑激酶介导细胞信号转导有关。