The experimental results showed that the PVRTg21 transgenic mice should possibly be an animal model for the neurovirulence evaluation of live poliomyelitis vaccines and epidemiological surveillance.

• 证明PVR Tg21小鼠可用作评价脊髓灰质炎活疫苗毒力试验的动物模型，也可用于病毒学和流行病学研究。