The establishment of the Western Regions Frontier Command indicated that the Western Han had begun to exercise state sovereignty over the Western Regions, and that Xinjiang had become a component part of the unitary multi-ethnic Chinese nation.

• 西域都护府的设立，标志着西汉开始在西域行使国家主权，新疆成为中国统一多民族国家的一个组成部分。