The detection of PrPSc in the BSE brains has become an important tool in the confirmation of BSE diagnosis and the immunohistochemical method is a gold standard of these detections.

• 患病牛脑中致病型朊蛋白的检测是诊断BSE的重要方法，其中免疫组织化学(immunohistochemistry，IHC)方法是检测的金标准。