The cytotoxin is an important fator in the pathogenesis of H. pylori, which induces vacuolation of epithelial cells and plays an important role in gastric epithelial necrosis and peptic ulceration.

• 该毒素是幽门螺杆菌重要的毒力致病因子，它的产生与感染者胃肠上皮损伤和溃疡形成密切相关。