The crosslinked chitosan resins were activated by 1,4-butanediol diglycidyl ether.The effect factors of activation were studied in detail and the reaction conditions were optimized.

• 采用1,4-二羟基正丁烷双缩水甘油醚活化交联壳聚糖树脂，偶联抗-乙型肝炎表面抗原单克隆抗体，制备树脂/抗体免疫吸附剂。