The concept,developed history and applications in agrochemicals discovery of bioisosterism were reviewed, and many examples of its successful applications were described in this paper.

• 本文简要叙述了生物等排的概念、发展史及其作为有效方法之一在新农药创制中的应用。文中给出许多运用生物电子等排成功开发的新农药实例。