The cirrhotic rats demon- strated obviously enhanced expression of AVP mRNA in hypothalamus and weakened AVP V1a receptor mRNA expression in renal cortex.

• 肝硬化大鼠下丘脑AVPmRNA水平明显升高，肾脏皮质V1a受体mRNA表达下调，可能与非渗透性因素有关。