The changes in rat plasma level of endothelin-ir (ET-ir) during CCl4-induced hepatic necrosis and the therapeutic action of ET-antiserum (ET Ab) were observed.

• 为探讨内皮素(ET)在肝坏死中的发病学意义；作者在四氯化碳(CCl_4)肝坏死模型上观察血浆ET-ir变化及其ET抗血清(ET-Ab)的治疗作用.