The anti-NKG2D pAb could obviously inhibit the cytotoxicity of NK cells towards K562 and HepG2 cells and decrease their cytotoxicity to both target cells for 6.7 and 4.1 times, respectively.

• 抗NKG2DpAb能显著抑制NK细胞对K5 6 2、HepG2细胞的细胞毒效应 ；使NK细胞对两种靶细胞的细胞毒效应分别下降了 6 .；7和 4