The aim of this study was to explore whether cyclosporine A(CsA)can modulate expression of MMP-9 and MMP-2 and invasion of the first-trimester human trophoblast cells.

• 本研究的目的是探讨环孢素A对人早孕期滋养细胞侵袭能力及基质金属蛋白酶9与2 (matrix metalloproteinase 9 and 2,简称MMP-9与MMP-2)表达的调节作用,为治疗反复自然流产等妊娠疾患提供新的线索。