The abnormal expression of oncoprotein P53 and P16 as well as the increase of telomerase are closely related to the occurrence and development of bowenoid papulosis.

• 感染细胞致癌蛋白p53和p16的异常表达、端粒酶活性的增高与鲍恩样丘疹病的发生发展密切相关。