The I/D polymorphism of ACE gene is not associated with essential hypertension, but DD genotype of ACE gene may be a risk forhypertensive kidney lesion.

• ACE基因I/D多态性与原发性高血压病的发病无密切相关但与高血压肾脏损害相关，ACE基因DD型可能是高血压肾脏损害的独立危险因素；