The A 431 antigen recognized by MoAb 3, 176 and 101 has an apparent molecular weight of approximately 170 000. It is a cell surface protein that can bind to above MoAbs in a number of human cell lines to a degree which parallels ECF binding.

• 对其中四株杂交瘤分泌的单克隆抗体进行了鉴定。 免疫沉淀放射自显影结果示单克隆抗体3、101和176均可识别A 431细胞膜抗原MW为170000的蛋白质即EGF受体。