Th e result showed that the transcription of prM gene caused intracellular immuniza tion, whether the prM protein was expressed or not.

• 3种重组质粒均可诱导细胞内免疫现象 ,说明无论是否表达prM蛋白 ,只要有prM基因转录就可引起细胞内免疫现象 ;