Tetramethylurea is synlhesed by phosgene.The optimum process conditions are consided.The content of product is 98% and the yield is 95.1%.

• 介绍了光气法合成四甲基脲的工艺路线；并对其进行了合成工艺研究；筛选出了最佳工艺条件；产品含量为98%25；收率为95.；1%25；为工业化生产提供了可靠的参考依据。