Ten prodrugs of moxifloxacin were synthesized via condensation of N tert butoxycarbnyl amino acids and moxifloxacin,hydrolysis to remove the N protecting groups and neutrolization.

• 分别以N-叔丁氧羰基氨基酸和莫西沙星为原料,经缩合、脱氨基保护基、中和得到8种含有氨基酰基的前药,按同样程序,还得到了2种含有二肽的前药。