Tamm-Horsfall protein (THP) has been considered as an inhibitor of some cyto-kines since it has been shown to be a high affinity ligand for IL-1, IL-2 and TNF.

• 近年在体外试验中证实,Tamm-Horsfall蛋白(THP)能以高度亲和力与IL-1、IL-2和TNF结合,故有作者提出,THP可能竞争与细胞因子结合,影响后者与受体的相互作用而发挥免疫抑制效应。