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- AIM:To investigate the feasibility of human cytidine deaminase gene(CD gene) transferred into mouse bone marrow cells and observe the tolerance of bone marrow cells to high dose arabinosylcytosine(Ara C). 目的:探讨人胞苷脱氨基酶基因(CD)导入小鼠骨髓细胞中,观察小鼠骨髓细胞对大剂量阿糖胞苷的耐受性。
- Short course high dose mitoxantrone with Ara C demonstrated a higher CR,lower mortality rate and can be applied in the treatment of refractory and relapsed acute leukemia. 短程大剂量米托蒽醌联合阿糖胞苷对难治复发急性白血病有较高的疗效 ,可提高缓解率 ,降低死亡率。
- Low dose Ara C or harringtonine were given in 16 elderly patients and the CR rate was 22.2%(4/18). 小剂量阿糖胞苷 (Ara C)或三尖杉脂碱 (H)化疗 18例 ;CR率 2 2 .;2%25 (4 18)。
- Conditioning regimens for second allo HSCT were combination chemotherapy based on moderate dose Ara C (n=5), Bu (n=3), conventional dose Ara C (n=1) and Flud/Mel (n=1). 第二次HSCT时预处理方案包括 :以中剂量阿糖胞苷 (Ara C)为主的联合化疗 5例 ; 以白消安为主的联合化疗 3例 ;
- DA? EA? COMP and HOAP regimens and small dose harringtonine or small dose Ara C were given to the patients according to their disease type and their relevant physical condition. 治疗以小到中剂量 HA、DA、EA、COMP及 HOAP等联合化疗或小剂量三尖杉酯碱、小剂量阿糖胞苷单药化疗。
- Supper high dose Ara-C 超大剂量阿糖胞苷
- Objective To investigate the mechanism of HHT and low dose arabinsyl cytosiwe (Ara c) inducing apoptosis of K562 cells. 目的 研究高三尖杉酯碱 (homoharringtonine,HHT)以及小剂量阿糖胞苷 (arabinsylcytosine,Ara C)联合诱导慢粒急变细胞株K5 6 2凋亡作用及其机制。
- Methods Cytotoxicity of Ara C was detected by the MTT assay. 方法采用MTT法检测Ara-C的细胞毒作用。
- Objective To study the therapeutic effect of vitamin C in high dose on hemodynamics and hemorheology when hemorrhagic shock induced. 目的探讨大剂量维生素C对休克时血液流变学及血流动力学的作用。
- Women, perhaps, could hazard a higher dose. 而女性呢,也许可以冒险试试更高一点的剂量。
- We treated eighteen patients with refractory acute lymphocyte leukemia with mitoxantrone, VP 16, Ara C (MEA) and extracted and analysed the nuclear matrix proteins by high salt and SDS PAGE before and after chemotherapty. 探索了用米托蒽醌、VP-16、阿糖胞苷联合化疗治疗难治性急性淋巴细胞白血病及其前后细胞核基质蛋白的变化。
- Can Sequential Administration Minimise the Cost of High Dose Chemotherapy? 循序行政管理能使高剂量化疗成本最小化吗?
- LDD ultra shallow junction can be reachec by low energy and high dose implant. 可以通过低能量,高剂量的等离子注入来实现LDD超浅结(ultra shallow junction)。
- The tolerance of bone marrow to Ara C was remarkably increased after transfected by drug resistance gene. 耐药基因转染后小鼠骨髓对阿糖胞苷的耐受明显增加。
- Melamine in high doses can disease kidney. 大剂量的三聚氰胺会导致肾病。
- CD gene can not only integrate and co express in mice bone marrow cells,but also increase the drug resistance to Ara C. CD基因可以进入小鼠骨髓细胞并且获得共表达,提高了造血细胞对阿糖胞苷的耐药性。
- Objective:To investigate the effect of ATRA on the apoptosis in HL 60 cells induced by Ara C. 目的 :探讨 HL- 6 0细胞经全反式维甲酸 (ATRA)作用后对化疗药物阿糖胞苷 (Ara- C)诱导凋亡敏感性的变化。
- ADR, VP16, CPT, MTX, Ara C could markedly induce apoptosis of Nalm 6 cells in S phase. ADR、VP16、CPT、MTX和Ara-C能明显诱导细胞凋亡,主要作用于S期。
- I forgive those ancestors who participated in the mass marketing of high dose supplements causing humans to become paranoid. 我意愿原谅参与大量营销那些令人类变得偏执狂的、高剂量营养补充品的所有祖先。
- This study was conducted to demonstrate the effect of IFN, HHT and Ara c eliminating CML Ph +cells. 为观察干扰素 (IFN)、高三尖杉酯碱 (HHT)及阿糖胞苷 (Ara- c)体外对慢性粒细胞性白血病(CML) Ph+ 细胞的生长影响 ,探讨其临床治疗 CML 的有效组合方案。