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- It is believed to be jump-started by a loss of neurons in a midbrain region called the substantia nigra. 相信这是可以跳开始，由一个亏损的神经元在中脑区称为黑质。
- The disease affects a small area of cells in the middle of the brain called the substantia nigra. 该疾病侵袭大脑中部一小部分被称为黑质的脑细胞。
- Many GABA-like positive fibres were observed at the inferior colliculus level of substantia nigra. 在下丘平面还可见到许多GABA样阳性神经纤维。
- No correlations were found in the volumes of the caudate, putamen, globus pallidus, substantia nigra with H&Y range. 结论：PD病人壳核体积大小与疾病严重程度呈负相关。
- It is caused by the death of nerve cells in a midbrain area called substantia nigra. 它是由于中脑塞梅林氏神经节中的神经细胞死亡导致的。
- Conclusions Passive smoking can partially protect DA neurons of substantia nigra from the damage of 6-OHDA. 结论被动吸烟可减轻6-OHDA对黑质DA能神经元的损伤。
- Parkinson's disease (PD) is a neurologic disorder characterized by dopaminergic cell death in the substantia nigra. 帕金森氏病（PD）是一种以黑质多巴胺能细胞死亡为特征的神经疾病。
- Conclusion Passive smoking can protect DA neurons of substantia nigra from the damage of 6-OHDA. 结论被动吸烟能减轻黑质纹状体DA能神经元的损伤。
- Initial results in a handful of patients suggested that symptoms had improved, and PET scans indicated some restoration in dopamine uptake in the striatum and substantia nigra. 这一小群患者的初步结果显示症状得到改善，而正子断层扫描则指出，纹状体与黑质多巴胺的吸收也有些进步。
- Surgeons insert a catheter into the left and right striatum, the main recipients in the basal ganglia of the dopamine secreted by neurons of the substantia nigra. 外科医师将导管伸入脑左右两边的纹状体，那里是接受黑质神经元释出多巴胺的主要基底核脑区。
- In many parkinson's cases, the damage can be seen in autopsies as clumps of proteins within the substantia nigra's dopaminergic neurons. 解剖许多帕金森氏症患者的尸体后发现，黑质多巴胺神经元中有堆积成块的蛋白质。
- Results In comparison with healthy group, SERT decreased in dorsal raphe nucleus, substantia nigra and striatum in PD brains. 结果与健康组比，PD人脑标本中缝背核、黑质以及纹状体的SERT标记信号呈不同程度降低。
- Objective: To observe the effect of electroacupuncture (EA) on the content of TH in mesencephalic substantia nigra (MSN) of PD rats. 目的 :观察电针对帕金森病大鼠黑质TH含量的影响。
- Conclusion Glutamate and GABA in the substantia nigra may affect iron metabolism through DMT1-IRE and HP in the caudate putamen nucleus. 结论 黑质的谷氨酸和GABA可能通过影响尾壳核DMT1-IRE和HP的表达影响纹状体尾壳核的铁代谢。
- Method：Model of hemilateral PD rat was established with injection of 6-hydroxydopamine（6-OHDA） into the substantia nigra of right side brain. 方法：采用6-羟基多巴胺（6-OHDA）注射于脑右侧黑质造成偏侧PD模型。
- We discuss the properties of substantia nigra dopamine neurons that might make them particular targets of such multiple hits. 以及抑制了神经元保护性应答，导致了选择的神经元死亡。
- Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of dopaminergic neurons in the substantia nigra. 帕金森氏病（PD）是一种神经退行性疾病，其特征为黑质的多巴胺能神经元变性。
- One injection of the factor into the striatum, prior to injection of the damage-inciting agent 6-OHDA, almost completely rescued dopaminergic neurons in the substantia nigra. 在注射致损伤药物6-羟基多巴胺之后，只需要向纹状体中注入一次保守型神经营养因子，就可以使黑质中的多巴胺能神经元几乎完全得以复苏。
- AIM: To compare the potencies between ( - )-stepholidine ((-)SPD) and 12-chloroscoulerine (CSL) enantiomers on firing of substantia nigra (SN) dopamine (DA.) neurons. 目的:比较左旋千金藤立定((-)-stepholidine,(-)-SPD)和12-氯斯阔任(12-chloroscoulerine,CSL)对黑质(substantia nigra,SN)多巴胺(DA)神经元放电的影响。
- Parkinson's disease arises from genetic and possibly neurotoxic causes that produce massive cell death of the neuromelanin-containing dopaminergic neurons of the substantia nigra. 帕金森氏病的病因包括基因突变和神经毒性物质作用，导致黑质多巴胺能神经元大量的死亡。
