Studies in AML have suggested that some human acute myeloid leukemias arise from neoplastic transformation at the level of pluripotent stem cells while others arise at much later stages, leading to a block in cell maturation.

• 白血病研究提示人急性粒细胞白血病是发生于多向干细胞水平的肿瘤性变,而另一些可发生在晚些阶段致细胞成熟停滞。