Start from acetanilide and 3chloro2methylpropionyl chloride, Pimobendan monohydrate was synthesized in 8 steps of reaction with a yield of 17.3%.

• 以乙酰苯胺和3－氯－2－甲基丙酰氯为起始原料，经8步反应即合成新型强心药匹莫苯（Pi－mobendan）单水合物，总收率达17.；3%25。