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- Sophoridine hydrochlorium 盐酸槐定碱
- Objection:To separate and identify the primary impurities in sophoridine. 目的:对槐定碱中主要微量杂质分离和鉴定。
- Objective To optimize the preparation process for preparing lung-targeted sophoridine(microsphere)(SR-MS). 目的优选肺靶向槐定碱白蛋白微球的制备工艺。
- Abstract:Objective To observe whether Sophoridine Hydrochloride for Injection has vascular stimulation,hemolyzation,agglutination and sensitization. 妇科恶性肿瘤是最常见的肿瘤之一,它严重影响了妇女的生活质量和生命时间。
- ResultsIt showed that the Sophoridine Hydrochloride for Injection had no vascular irritation and injury effect on rabbit vascular endothelial cell. 与同类产品比较,可明显降低患者治疗痛苦和辅助治疗的经济负担。
- Oxymartrine and low dose group of Sophoridine could significantly prolong the latencies of epileptic seizure, and reduced seizure degree compared with penicillin group. 结果与致痫组相比氧化苦参碱低、高剂量组和槐定碱低剂量组均能不同程度地延长痫性发作潜伏期,并且降低痫性发作程度;
- Methods:Using column chromatography method to separate the unknown impurities from the crude sophoridine,then analysing and identifing its structure through HPLC,IR,SXRD. 方法:采用柱层析法从槐定碱粗品中分离得到未知杂质,通过HPLC、IR、单晶X-射线衍射法分析鉴定其结构。
- The study investigated the influences of Oxymartrine and Sophoridine on epilepsy using the methods of behavior evaluation and morphology.Results The epilepsy model was successful. 大鼠腹腔注射大剂量青霉素致痫模型,并腹腔注射氧化苦参碱和槐定碱,观察其行为学和海马组织形态学改变。
- After using Oxymartrine and Sophoridine, neuron tumefaction and organelle damnification could be improved, conclusion Oxymartrine and low dosage Sophoridine have certain of protection to brain damage. 结论氧化苦参碱和小剂量槐定碱对脑组织损伤有一定的保护作用。
- Keywords sophoridine;hypnosic action;convulsion; 槐定碱;催眠作用;惊厥;
- Sophoridine Hydrochloride for Injection 注射用盐酸槐定碱
- Keywords sophoridine;N-Succinyl-chitosan;microsphere;processte chnology; 槐定碱;N-琥珀酰壳聚糖;微球;制备工艺;
- Determination of the Ionization Constant of Sophoridine by the Spectrophotometric Indicator Method 分光光度指示剂法测定槐定碱的电离常数
- Keywords Saphora alopecurodies;sophoridine;matrine;sophocarpine;quality determination; 苦豆子总碱;槐定碱;苦参碱;槐果碱;含量测定;
- Keywords Sophoridine Hydrochloride for Injection;Stimulation of vas cular;Hemolysis;ASA;PCA; 注射用盐酸槐定碱;血管刺激;溶血;全身主动过敏反应;被动皮肤过敏;
- Keywords Sophoridine;sophocarpine;matrine;Kuhuang injection;high performance liquid chromatography-mass spectrometry;pharmacokinetics; 槐定碱;槐果碱;苦参碱;苦黄注射液;液-质联用;药代动力学;
- sophoridine 槐定, 槐定碱