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- This process resulted in1,307 confirmed somatic mutations in1,149 genes. 该过程发现1149个基因的1307种被证实的体细胞突变。
- Heteroplasmy is a common phenomenon in mitochondrial DNA somatic mutations of human tumors. 认为胞质异质性是人类肿瘤组织线粒体基因突变的普遍现象。
- Most somatic mutations are likely to be 'passengers' that do not contribute to oncogenesis. 大多数的体细胞突变仅仅像是过客而不引起肿瘤发生。
- Bioinformatics was applied to analyses of recombination patterns,somatic mutations and germline gene segments usage,and to prediction of epitopes recognized by CTL. 利用生物信息资源分析B ALLIgHV基因重排类型、胚系基因片段利用及体细胞突变情况 ,并预测CTL细胞识别的表位。
- We did not detect any somatic mutation in PTCH gene. 追踪四个月并无复发的迹象。
- BACKGROUND & OBJECTIVE: Recent studies showed that somatic mutations in epidermal growth factor receptor (EGFR) tyrosine kinase (TK) domain are assoc iated with sensitivity of non-small cell lung cancer(NSCLC) to TK inhibitor gefi tinib. 背景与目的:最近的研究结果表明,表皮生长因子受体(epidermalgrowthfactorreceptor,EGFR)基因酪氨酸激酶域的体细胞突变与非小细胞肺癌(non鄄smallcelllungcancer,NSCLC)患者对酪氨酸激酶抑制剂吉非替尼的敏感性密切相关。
- Results: Observation 4 cases with somatic mutation have clinical effect. 结果发现4例体细胞突变均有临床效应;
- Genomic instability involving structure alterations and epigenetic effect stems from germline and somatic mutation and related to genetic susceptibility of cancer. 基因组不稳定性与癌的遗传易感性相关,涉及基因组结构改变和表遗传效应,来源于胚系突变和体细胞突变。
- Conclusion: Somatic mutation may be caused by reproduction cell chromosome structural rearrangement.and genetic docter should deserve attention in clinic. 结论临床中散在的单个细胞染色体畸变可能发生在生殖细胞中,应引起遗传医师的重视。
- For example, plants can sometimes transmit somatic mutations to their descendants asexually or sexually where flower buds develop in somatically mutated parts of plants. 例如，植物有时将体细胞突变通过无性或有性过程传递给后代，而花芽可能由植物的体细胞变异部分发育。
- At the same time, the information of flax biotechnology of anther culture, haploid breeding, utilization of somatic mutation, protoplasmic culture, gene transformation were introduced in detail. 从亚麻花药培养、单倍体育种、体细胞无性系突变体的利用、原生质体培养、转基因技术的研究等方面详细地介绍了我国亚麻生物技术的发展状况。
- Mitochondrial DNA somatic mutations and germline variations in patients with esophageal cancer 食管癌线粒体DNA体细胞性突变与种系性变异
- somatic mutation theory of cancer 癌体细胞突变学说
- The mutations in plants caused by radiation have been found in experiments. 放射线引起植物变异已在实验中被证实。
- Somatic cell hybridization is technique. 体细胞杂交是一种技术。
- Most of these mutations are harmless. 大部分的基因突变是没有害处的。
- Mutations in the ABCA 1 gene cause Tangier disease. ABCA 1基因的突变引起Tangier病 (TD)。
- Somatic Embryogenesis of Aesculus hippocastanum L. 欧洲七叶树体细胞胚胎发生研究。
- The capsules were examined for genetic mutations. 这些胶囊用于检测基因突变。
- Gene mutations are alterations in the DNA code. 基因突变是指DNA 密码的改变。
