Solvation effects of four isomerization reactions have been inverstigated by using the TLSER model, The good correlation of QSPR equations verify the reasonability of the model.

• 并用该模型对四类异构化反应在不同溶剂下的反应自由能或活化自由能与溶剂的分子结构之间的关系进行了研究，确证了模型的合理性。