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- The ranolazine works by blocking what is called delayed inward sodium current. 雷诺嗪的作用机制是阻断迟发性钠离子内流。
- Methods Whole cell patch clamp technique was used to test the effects of Pho and Fen on TTX-S and TTX-R sodium currents in DRG neurons. 方法应用膜片钳技术研究氰戊菊酯和辛硫磷对DRG河豚毒素敏感(TTX-S)和不敏感(TTX-R)型钠通道的作用。
- ConclusionLoureirin B significantly inhibits the TTX-R sodium currents and perhaps the inhibition is one of the ease pain mechanism of Loureirin B. 结论龙血素B显著抑制TTX-R钠电流,且这种抑制作用发生在钠通道的失活过程而非激活过程,这种作用可能是其镇痛作用的机理之一。
- There was no any effect of Pho on the TTX-S and TTX-R sodium channels.The mixed treatment of a Pho and Fen did not show joint effect on the sodium currents. 辛硫磷对这两种亚型钠通道无明显影响,将氰戊菊酯和辛硫磷混配使用后,仅见氰戊菊酯作用的表现,未见氰戊菊酯和辛硫磷的联合作用。
- Under whole-cell patch-clamp recording, sodium current (INa) was activated when the voltage was around -60 mV, and the peak current occurred at about +10 mV. 在全细胞电压钳条件下,神经细胞Na+通道电流(INa)在-60mV左右激活,+10mV左右达峰值,对河豚毒素敏感。
- The present study was to investigate the changes of TTX R sodium currents and NaN/SNS2 sodium channel transcripts in DRG neurons in chronic constriction injury (CCI) of sciatic nerve 14 days after surgery. 目的 :观察电压门控钠通道NaN /SNS2在大鼠坐骨神经慢性压迫性损伤 (chronicconstric tioninjury ,CCI) 14天后的变化 ,探讨慢性神经痛的发生机制。
- Aim To investigate the effects of imidapril (IMI) on effective refractory period (ERP) and sodium current (I_(Na)) of myocytes in ventricular noninfarction zone of healed myocardial infarction (HMI) in rabbit models. 目的探讨咪达普利(IMI)对家兔陈旧性心梗(HMI)后心脏有效不应期(ERP)及钠电流(I_(Na))的影响。
- Keywords brucine;sodium current;hippocampal neuron; 马钱子碱;钠通道;海马神经元;
- Sodium and water react (together). 钠和水能起反应。
- Keywords voltage-gated sodium currents;patch;neuron;peroxynitrite; 电压门控钠通道电流;膜片钳;神经元;过氧亚硝酸;
- Demand is outstripping current production. 现在需求逐渐超过了生产能力。
- She broadcasts on current affairs. 她发表时事广播演说。
- Common salt is a compound of sodium and chlorine. 食盐是钠和氯的化合物。
- Our language goes current along the seacoast. 我们的语言通用于沿海一带。
- You may open a current account at a bank. 你可以在银行开立一个活期帐户。
- I'd like to open a current account with you. 我想在你们这儿开一个活期存款帐户。
- In convection, hot currents flow upwards. 在对流中热气流向上运动。
- Dangerous currents can suck swimmers under. 险急的水流能把游泳的人吞没。
- Persistent Sodium Current and Cellular Ischemia and Hypoxia 持续性钠电流与细胞缺血缺氧
- He made some comments on current topics. 他对时事问题做了若干的评论。