Since the zero-order release and the first-order release are the primary release patterns, the theory should be a key to explore the pharmacokinetics of the controlled/sustained release dosage forms.

• 由于零级释放与一级释放是基本的释放模式,零级释放和一级释放药物动力学理论是建立和理解缓释、控释制剂药物动力学的基础。