Signals mediated through these pathways critically determine the frequency of circulating monocyte subsets and thereby account for almost all macrophage accumulation into atherosclerotic arteries.

• 介导的信号通过这些通路精密地决定循环中单核细胞亚型的表达频率，从而解释了几乎所有动脉粥样硬化的动脉中巨噬细胞的聚集现象。