Sex chromosome lose is the most frequent extral abnormity of t (8; 21) AML,and is predominantly associated with M2 subtype of AML with unique morphological,immunological and clinical features,

• 性染色体丢失是t(8;21)急性髓系白血病最常见的附加异常,主要和急性粒细胞白血病有关,具有独特的形态学、免疫学和临床特征。