Seventy-five patients received CMF:CTX600mg/m2 iv in bolus on day 1, MTX 40mg/ m2 iv in bolus on day1 ,and 5-FU600mg/m iv drip on day 1-5;

• 另外75例接受CMF方案治疗,CTX600mg/m~2静推第1天,MTX40mg/m~2静推第1天,5-Fu600mg/m~2静脉滴注第1至第5天。