Seventy five patients received CMF:cyclophosphamide 600mg/m 2 iv on day 1,methotrexate 40mg/m 2 iv on day 1,and 5 fluorouracil 600mg/m 2 iv on day 1.Three therapeutic courses were given with an interval of 21 days.

• 另外 75例接受CMF方案 ,CTX 6 0 0mg/m静推第 1天 ,MTX 40mg/m静推第 1天 ,5 FU 6 0 0mg/m静滴第 1天 ,均应用三周期以上。